Pranav Khade
Scientist, Computational Biologics Design Gilead Sciences
Seminars
Thursday 27th August 2026
Application of AI/ML for Predicting CIEX Binding Differences of mAb Building Blocks
2:00 pm
- Sequence pI, the most widely used CIEX binding predictor is a poor predictor of binding to CIEX
- LLM descriptors can be used to predict aCIEX retention time
- 100s of aCIEX data points and their sequence, structure and pLLM based features can be leveraged for selecting and/or designing mAb building blocks
