David Longo
Chief Executive Officer Ordaos Bio
David Longo is the Co-Founder and Chief Executive Officer (CEO) of Ordaōs. As CEO of Ordaōs, Longo leads a strong scientific team to design novel mini-proteins that help drug hunters deliver safer and more effective treatments.
Longo brings to Ordaōs, broad experience in innovation and technology, that compel him to approach protein design in a unique way. His expertise in AI and machine learning is incorporated into Ordaōs’ Design Engine, driving the rapid creation of never-before-seen mini-proteins with improved probability of more therapeutically effective candidates. Prior to Ordaōs, this entrepreneur led a series of companies which he grew into successful entities.
Longo has an MS in biotechnology from Harvard University, graduate certificates in AI, Machine Learning, Innovation and Technology from Stanford University and Massachusetts Institute of Technology (MIT), and a master’s Certificate in Music Production from Berklee College of Music. He has a Bachelor of Science in Computational Mathematics from Rochester Institute of Technology. David is a learner, triathlete, and an inspirational leader.
Seminars
- Exploring how an adversarial generation engine with continuous in silico evaluation dynamically steers de novo miniprotein design to improve multi-objective hit rates
- Discussing the use of labelled design and click chemistry–based modular assembly to enable efficient scaling from single miniproteins and VHHs to multispecific constructs
- Identifying informative labels using model heuristics to bias generative sampling towards optimized affinity, specificity, stability, and immunogenicity profiles
